Terms & Properties

Preferred Name:  Breast Inflammatory Carcinoma

Definition:  An advanced, invasive breast adenocarcinoma characterized by the presence of distinct changes in the overlying skin. These changes include diffuse erythema, edema, peau d'orange (skin of an orange) appearance, tenderness, induration, warmth, enlargement, and in some cases a palpable mass. The skin changes are the consequence of lymphatic obstruction from the underlying invasive breast adenocarcinoma. Microscopically, the dermal lymphatics show prominent infiltration by malignant cells. The invasive breast adenocarcinoma is usually of ductal, NOS type. There is not significant inflammatory cell infiltrate present, despite the name of this carcinoma.

NCI-GLOSS Definition:  A type of breast cancer in which the breast looks red and swollen and feels warm. The skin of the breast may also show the pitted appearance called peau d'orange (like the skin of an orange). The redness and warmth occur because the cancer cells block the lymph vessels in the skin.

Display Name:  Inflammatory Breast Carcinoma

Label:  Breast Inflammatory Carcinoma

NCI Thesaurus Code:  C4001 (Search for linked caDSR metadata)   (search value sets)

NCI Metathesaurus Link:  C0278601  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

Breast Inflammatory Carcinoma

Inflammatory Breast Cancer

inflammatory breast cancer

Inflammatory Breast Carcinoma

Inflammatory breast carcinoma

Inflammatory carcinoma

Inflammatory Carcinoma of Breast

Inflammatory Carcinoma of the Breast

Mastitis Carcinomatosa

External Source Codes: 

UMLS CUI

C0278601

Other Properties:

Name	Value (qualifiers indented underneath)
code	C4001
Contributing_Source	Cellosaurus
Contributing_Source	CTEP
Contributing_Source	CTRP
Contributing_Source	GDC
ICD-O-3_Code	8530/3
Legacy Concept Name	Inflammatory_Breast_Carcinoma
Maps_To	8530/3
	Target_Terminology: GDC       Relationship_to_Target: Related To       Target_Term_Type: PT       Target_Code: morphology
Maps_To	Inflammatory carcinoma
	Target_Terminology: ICDO3       Target_Terminology_Version: 3.1       Relationship_to_Target: Related To       Target_Term_Type: PT       Target_Code: 8530/3
Maps_To	Inflammatory carcinoma
	Target_Terminology: ICDO3       Target_Terminology_Version: 3.2       Relationship_to_Target: Related To       Target_Term_Type: PT       Target_Code: 8530/3
Maps_To	Inflammatory carcinoma
	Target_Terminology: GDC       Relationship_to_Target: Has Synonym       Target_Term_Type: PT       Target_Code: primary_diagnosis
Neoplastic_Status	Malignant
Semantic_Type	Neoplastic Process

Additional Concept Data: 

Defined Fully by Roles: Yes

URL:https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C4001