|Osteoporosis (Code C3298)|
|Terms & Properties|
Preferred Name: Osteoporosis
Definition: A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).
NCI-GLOSS Definition: A condition that is marked by a decrease in bone mass and density, causing bones to become fragile.
NICHD Definition: Reduced bone mineral density due to decreased number and thickness of bone trabeculae and decreased cortical thickness, associated with increased risk of skeletal fractures. A clinical diagnosis of osteoporosis in childhood requires either a finding of one or more otherwise unexplained vertebral compression fractures, or the presence of bone mineral density Z-score less than or equal to 2.0 accompanied by one or more of the following: 1) at least two long bone fractures by age 10 years; 2) at least three long bone fractures up to age 19 years.
CTCAE Definition: A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence.
Display Name: Osteoporosis
NCI Metathesaurus Link: C0029456 (see NCI Metathesaurus info)
Synonyms & Abbreviations: (see Synonym Details)
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|Defined Fully by Roles: No|