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Version: 17.10e (Release date: 2017-10-30)
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Osteoporosis (Code C3298)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Osteoporosis

Definition: A condition of reduced bone mass, with decreased cortical thickness and a decrease in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence. Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).

NCI-GLOSS Definition: A condition that is marked by a decrease in bone mass and density, causing bones to become fragile.

NICHD Definition: Reduced bone mineral density due to decreased number and thickness of bone trabeculae and decreased cortical thickness, associated with increased risk of skeletal fractures. A clinical diagnosis of osteoporosis in childhood requires either a finding of one or more otherwise unexplained vertebral compression fractures, or the presence of bone mineral density Z-score less than or equal to 2.0 accompanied by one or more of the following: 1) at least two long bone fractures by age 10 years; 2) at least three long bone fractures up to age 19 years.

CTCAE Definition: A disorder characterized by reduced bone mass, with a decrease in cortical thickness and in the number and size of the trabeculae of cancellous bone (but normal chemical composition), resulting in increased fracture incidence.

Display Name: Osteoporosis

Label: Osteoporosis

NCI Thesaurus Code: C3298 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0029456  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Osteoporosis
osteoporosis

External Source Codes: 
UMLS CUI C0029456

Other Properties:
     Name Value (qualifiers indented underneath)
code C3298
Contributing_Source CTRP
Contributing_Source NICHD
Legacy_Concept_Name Osteoporosis
NICHD_Hierarchy_Term Osteoporosis
Semantic_Type Disease or Syndrome

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&ns=ncit&code=C3298

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