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Version: 17.06d (Release date: 2017-06-26)
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North American Ginseng Extract AFX-2 (Code C99122)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: North American Ginseng Extract AFX-2

Definition: An orally available proprietary aqueous extract from the North American ginseng (Panax quinquefolius) dried root, primarily containing poly-furanosyl-pyranosyl-saccharides, with potential immunostimulating activity. Upon administration, North American ginseng extract AFX-2 may stimulate the proliferation and activation of B-lymphocytes and stimulates IgG production by B cells. Also, this agent induces maturation of dendritic cells, induces T cell proliferation and activates peritoneal exudate macrophages leading to an increase in the production of the cytokines interleukin -1 and -6, tumor necrosis factor-alpha, interferon-gamma and nitric oxide.

Label: North American Ginseng Extract AFX-2

NCI Thesaurus Code: C99122 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1722695  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AFX-2
COLD-fX
CVT-E002
North American Ginseng Extract AFX-2
Panax quinquefolius Extract AFX-2

External Source Codes: 
PDQ Closed Trial Search ID 715600
PDQ Open Trial Search ID 715600 (check for NCI PDQ open clinical trial info)
UMLS CUI C1722695

Other Properties:
     Name Value (qualifiers indented underneath)
code C99122
Semantic_Type Pharmacologic Substance
Semantic_Type Plant

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C99122

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