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Version: 17.06d (Release date: 2017-06-26)
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Acodazole (Code C988)

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Terms & Properties

Preferred Name: Acodazole

Definition: A synthetic imidazoquinoline with antineoplastic activity. Acodazole intercalates into DNA, resulting in disruption of DNA replication. Use of this agent has been associated with significant cardiotoxicity. (NCI04)

Label: Acodazole

NCI Thesaurus Code: C988 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0050565  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1H-imidazo[4,5-f]quinoline, acetamide deriv
acetamide, N-methyl-N-[4-[(7-methyl-1H-imidazo[4, 5-f]quinolin-9-yl)amino]phenyl]-

External Source Codes: 
CAS Registry Number 79152-85-5 (see NLM ChemIDplus info)
FDA UNII Code 8M28A9O41G
PDQ Closed Trial Search ID 39786
PDQ Open Trial Search ID 39786 (check for NCI PDQ open clinical trial info)
UMLS CUI C0050565

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C20H19N5O
code C988
Contributing_Source FDA
Legacy_Concept_Name Acodazole
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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