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Version: 17.06d (Release date: 2017-06-26)
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4-Nitroestrone 3-Methyl Ether (Code C977)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: 4-Nitroestrone 3-Methyl Ether

Definition: A synthetic derivative of estradiol. 4-nitroestrone 3-methyl ether inhibits estrogen sulfotransferase (EST), a progesterone-induced secretory endometrial enzyme which affects estrogen receptor levels. This agent has been shown to be an effective growth inhibitor of some chemically induced animal mammary tumors. (NCI04)

Label: 4-Nitroestrone 3-Methyl Ether

NCI Thesaurus Code: C977 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0048573  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
4-Nitroestrone
4-Nitroestrone 3-methyl ether
4-Nitroestrone 3-Methyl Ether

External Source Codes: 
CAS Registry Number 14846-62-9 (see NLM ChemIDplus info)
NSC Code 321803 (see NCI DTP info)
PDQ Closed Trial Search ID 39339
PDQ Open Trial Search ID 39339 (check for NCI PDQ open clinical trial info)
UMLS CUI C0048573

Other Properties:
     Name Value (qualifiers indented underneath)
code C977
Legacy_Concept_Name _4-Nitroestrone_3-Methyl_Ether
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C977

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