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Version: 17.08d (Release date: 2017-08-28)
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Brain Tumor Initiating Cell Vaccine (Code C97666)

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Terms & Properties

Preferred Name: Brain Tumor Initiating Cell Vaccine

Definition: A cell-based cancer vaccine comprised of brain tumor initiating cells (BTICs), with potential immunostimulating and antineoplastic activity. BITCs are from the glioblastoma multiforme (GBM) cell line GBM-6 and contain glioma stem-like cell-associated antigens. Upon administration, the BITC vaccine may stimulate a specific anti-tumoral cytotoxic T-lymphocyte (CTL) response against brain tumor cancer cells and brain tumor stem like cells, resulting in tumor cell lysis. BITC have unique antigenicity and have the ability to self-renew; vaccination against BITC antigens may kill these cells and may prevent tumor recurrences.

Display Name: Brain Tumor Initiating Cell Vaccine

Label: Brain Tumor Initiating Cell Vaccine

NCI Thesaurus Code: C97666 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL430321  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Brain Tumor Initiating Cell Vaccine
BTIC Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 706828
PDQ Open Trial Search ID 706828 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C97666
Contributing_Source CTRP
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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