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Version: 17.06d (Release date: 2017-06-26)
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Ipomeanol (Code C976)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Ipomeanol

Definition: A natural toxic furan isolated from a fungus-infected sweet potato (Ipomoea batatas) with potential antineoplastic activity. Ipomeanol is activated by mixed function oxidases in vivo to its epoxide form, an alkylating agent that covalently binds cell macromolecules. This agent causes cell death by a p53-independent mechanism. (NCI04)

Label: Ipomeanol

NCI Thesaurus Code: C976 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0048420  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1-(3-Furanyl)-4-hydroxy-1-pentanone
1-(3-furanyl)-4-hydroxy-1-pentanone
1-Pentanone, 1-(3-furanyl)-4-hydroxy-
4-ipomeanol
4-Ipomeanol
Ipomeanol

External Source Codes: 
CAS Registry Number 32954-58-8 (see NLM ChemIDplus info)
NSC Code 349438 (see NCI DTP info)
PDQ Closed Trial Search ID 38852
PDQ Open Trial Search ID 38852 (check for NCI PDQ open clinical trial info)
UMLS CUI C0048420

Other Properties:
     Name Value (qualifiers indented underneath)
code C976
Legacy_Concept_Name Ipomeanol
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C976

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