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Version: 17.06d (Release date: 2017-06-26)
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Famitinib (Code C97512)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Famitinib

Definition: An orally bioavailable receptor tyrosine kinase (RTK) inhibitor with potential antineoplastic activity. Famitinib binds to and inhibits several RTKs, dysregulated in a variety of tumors, including stem cell factor receptor (c-Kit; SCFR), vascular endothelial growth factor receptor (VEGFR) 2 and 3, platelet-derived growth factor receptor (PDGFR) and FMS-like tyrosine kinases Flt1 and Flt3. Inhibition of these RTKs may result in an inhibition of tumor growth and angiogenesis, and eventually tumor regression in tumor cells overexpressing these RTKs.

Label: Famitinib

NCI Thesaurus Code: C97512 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C3273460  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Famitinib

External Source Codes: 
PDQ Closed Trial Search ID 703815
PDQ Open Trial Search ID 703815 (check for NCI PDQ open clinical trial info)
UMLS CUI C3273460

Other Properties:
     Name Value (qualifiers indented underneath)
code C97512
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C97512

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