skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Afimoxifene (Code C975)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Afimoxifene

Definition: A tamoxifen metabolite with both estrogenic and anti-estrogenic effects. Afimoxifene has a higher affinity for the estrogen receptor than tamoxifen, and functions as an antagonist in breast cancer cells.

NCI-GLOSS Definition: A form of the drug tamoxifen that is made by the body after taking tamoxifen. It can also be made in the laboratory, and may help decrease breast density. A topical form of 4-hydroxytamoxifen is being studied in breast cancer screening.

Display Name: Afimoxifene

Label: Afimoxifene

NCI Thesaurus Code: C975 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2347999  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)

External Source Codes: 
CAS Registry Number 68047-06-3 (see NLM ChemIDplus info)
CAS Registry Number 68392-35-8 (see NLM ChemIDplus info)
FDA UNII Code 17197F0KYM
ChEBI ID CHEBI:44616 (see ChEBI info)
PDQ Closed Trial Search ID 371709
PDQ Open Trial Search ID 371709 (check for NCI PDQ open clinical trial info)
UMLS CUI C2347999

Other Properties:
     Name Value (qualifiers indented underneath)
code C975
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name _4-Hydroxy-Tamoxifen
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


Mainbox Bottom