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Version: 17.08d (Release date: 2017-08-28)
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5-Fluorouracil/Salicylic Acid Topical Solution (Code C97131)

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Terms & Properties

Preferred Name: 5-Fluorouracil/Salicylic Acid Topical Solution

Definition: A topical formulation containing 0.5 % of antimetabolite 5-fluorouracil (5-FU) and 10% of salicylic acid, with potential antimitotic and keratolytic activity. Upon cutaneous application, 5-FU in the 5-fluorouracil/salicylic acid topical solution impedes pyrimidine metabolism thereby inhibiting cell growth, while the salicylic acid induces anti-inflammatory response and results in keratolytic effect. This may result in the breakdown of keratinocytes and prevent proliferation of keratinocytes locally.

Label: 5-Fluorouracil/Salicylic Acid Topical Solution

NCI Thesaurus Code: C97131 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL429685  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
5-Fluorouracil/Salicylic Acid Topical Solution
Actikerall
LAS 41005
Low-dose 5-Fluorouracil/Salicylic Acid

External Source Codes: 
PDQ Closed Trial Search ID 701314
PDQ Open Trial Search ID 701314 (check for NCI PDQ open clinical trial info)
NCI META CUI CL429685

Other Properties:
     Name Value (qualifiers indented underneath)
code C97131
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C97131

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