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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Radiosensitizer RRx-001 (Code C97130)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Radiosensitizer RRx-001

Definition: A dinitroazetidine derivative with potential radiosensitizing activity. Upon administration, RRx-001 is able to dilate blood vessels, thereby increasing tumor blood flow and thus improving oxygenation to the tumor site. By increasing oxygen levels, these tumor cells may be more susceptible to radiation therapy. Tumor hypoxia is correlated with tumor aggressiveness, metastasis and resistance to radiotherapy.

Display Name: Radiosensitizer RRx-001

Label: Radiosensitizer RRx-001

NCI Thesaurus Code: C97130 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C3273246  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Radiosensitizer RRx-001
RRx-001

External Source Codes: 
PDQ Closed Trial Search ID 701311
PDQ Open Trial Search ID 701311 (check for NCI PDQ open clinical trial info)
UMLS CUI C3273246

Other Properties:
     Name Value (qualifiers indented underneath)
code C97130
Contributing_Source CTRP
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C97130

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