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Version: 17.06d (Release date: 2017-06-26)
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Technetium Tc 99m Galactosyl Human Serum Albumin (Code C97036)

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Terms & Properties

Preferred Name: Technetium Tc 99m Galactosyl Human Serum Albumin

Definition: A colloid formulation of human galactosyl serum albumin (GSA) conjugated to the chelating agent diethylene-triaminepentaacetic acid (DTPA) and complexed to the gamma-emitting isotope technetium-99m (99mTc-GSA) with potential diagnostic imaging activity. Upon intravenous administration, the galactosyl moiety of 99mTc-GSA binds to asialoglycoprotein receptors (ASGPR) located on hepatic cells. Upon SPECT (Single Photon Emission Computed Tomography) imaging, liver function can be assessed. The expression of asialoglycoprotein receptors (ASGPR), which are solely found on the plasma membrane of mammalian hepatocytes, is associated with hepatic function.

Label: Technetium Tc 99m Galactosyl Human Serum Albumin

NCI Thesaurus Code: C97036 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL429643  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
99mTc-GSA
Tc-99m GSA
Technetium Tc 99m Galactosyl Human Serum Albumin

External Source Codes: 
PDQ Closed Trial Search ID 700541
PDQ Open Trial Search ID 700541 (check for NCI PDQ open clinical trial info)
NCI META CUI CL429643

Other Properties:
     Name Value (qualifiers indented underneath)
code C97036
Semantic_Type Indicator, Reagent, or Diagnostic Aid
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C97036

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