skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
MAGE-A3 Reactive T Cell Receptor-transduced Autologous T Cells (Code C97035)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: MAGE-A3 Reactive T Cell Receptor-transduced Autologous T Cells

Definition: Human autologous T-lymphocytes transduced with a retroviral vector encoding a T cell receptor (TCR) specific for the human melanoma antigen A3 (MAGE-A3), with potential antineoplastic activity. Upon isolation, transduction, expansion ex vivo, and reintroduction into the patient, the MAGE-A3 reactive TCR-transduced autologous T cells bind to tumor cells expressing MAGE-A3, which may halt the growth of MAGE-A3-expressing cancer cells; the TCR is specific for MAGE-A3:168-176.

Display Name: MAGE-A3 Reactive T Cell Receptor-transduced Autologous T Cells

Label: MAGE-A3 Reactive T Cell Receptor-transduced Autologous T Cells

NCI Thesaurus Code: C97035 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL429642  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
MAGE-A3 Reactive T Cell Receptor-transduced Autologous T Cells
MAGE-A3 TCR-transduced Autologous T cells

External Source Codes: 
PDQ Closed Trial Search ID 700454
PDQ Open Trial Search ID 700454 (check for NCI PDQ open clinical trial info)
NCI META CUI CL429642

Other Properties:
     Name Value (qualifiers indented underneath)
code C97035
Contributing_Source CTRP
Semantic_Type Cell
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C97035

Mainbox Bottom