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Version: 17.06d (Release date: 2017-06-26)
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Iobenguane I-131 (Code C970)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Iobenguane I-131

Definition: An I 131 radioiodinated synthetic analogue of the neurotransmitter norepinephrine. Iobenguane localizes to adrenergic tissue and, in radioiodinated forms, may be used to image or eradicate tumor cells that take up and metabolize norepinephrine.

NCI-GLOSS Definition: A radioactive substance that is used in imaging tests, and is being studied in the treatment of cancer. It is a type of radiopharmaceutical.

Display Name: Iobenguane I-131

Label: Iobenguane I-131

NCI Thesaurus Code: C970 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0879568  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(131)I-MIBG
131I-MIBG
I-131 Metaiodobenzylguanidine
Iobenguane I-131
IOBENGUANE I-131
iodine I 131 metaiodobenzylguanidine
Iodine I 131 Metaiodobenzylguanidine
I 131 Meta-iodobenzylguanidine
MIBG I-131

External Source Codes: 
CAS Registry Number 77679-27-7 (see NLM ChemIDplus info)
FDA UNII Code Q461L7AK4R
PDQ Closed Trial Search ID 38020
PDQ Open Trial Search ID 38020 (check for NCI PDQ open clinical trial info)
UMLS CUI C0879568

Other Properties:
     Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Diagnostic imaging; Neuroendocrine tumors.
Chemical_Formula C8H10IN3
code C970
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Meta-Iodobenzylguanidine
Semantic_Type Indicator, Reagent, or Diagnostic Aid
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C970

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