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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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Copanlisib (Code C96796)

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Terms & Properties

Preferred Name: Copanlisib

Definition: A phosphoinositide 3-kinase (PI3K) inhibitor with potential antineoplastic activity. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents.

Display Name: Copanlisib

Label: Copanlisib

NCI Thesaurus Code: C96796 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C3852004  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
BAY 80-6946
PI3K Inhibitor BAY 80-6946

External Source Codes: 
PDQ Closed Trial Search ID 653981
PDQ Open Trial Search ID 653981 (check for NCI PDQ open clinical trial info)
UMLS CUI C3852004

Other Properties:
     Name Value (qualifiers indented underneath)
code C96796
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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