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Version: 17.06d (Release date: 2017-06-26)
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Topical Piperidine Nitroxide MTS-01 (Code C96428)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Topical Piperidine Nitroxide MTS-01

Definition: A topical gel containing a cell permeable hydrophilic piperidine nitroxide with potential radioprotective and antioxidant activity. As a stable, free radical compound, MTS-01 may be able to protect cells against the damaging effects of reactive oxygen species (ROS), upon exposure to ionizing radiation and oxidative stress. The topically applied MTS-01 may protect normal tissue from radiation-induced toxicity, such as radiation dermatitis, during radiation therapy.

Display Name: Topical Piperidine Nitroxide MTS-01

Label: Topical Piperidine Nitroxide MTS-01

NCI Thesaurus Code: C96428 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0045283  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
1-Piperidinyloxy, 4-Hydroxy-2,2,6,6-tetramethyl-
4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
MTS-01
TEMPOL
Tempol
Topical Piperidine Nitroxide MTS-01

External Source Codes: 
CAS Registry Number 2226-96-2 (see NLM ChemIDplus info)
FDA UNII Code U78ZX2F65X
PDQ Closed Trial Search ID 698263
PDQ Open Trial Search ID 698263 (check for NCI PDQ open clinical trial info)
UMLS CUI C0045283

Other Properties:
     Name Value (qualifiers indented underneath)
code C96428
Contributing_Source CTRP
Contributing_Source FDA
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C96428

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