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Version: 16.11d (Release date: 2016-11-28)
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18-F-fluoroacetate (Code C96236)

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Terms & Properties

Preferred Name: 18-F-fluoroacetate

Definition: A radioconjugate and an acetate analog labeled with fluorine F 18 ((18)F-FAC), a positron-emitting isotope, with potential prostate tumor tracer property using positron emission tomography (PET). Although the mechanism of action is unclear, fluorine F 18 acetate preferentially accumulates in tumor tissue, serving as a tracer for imaging tumors with PET. Fluorine 18 has a longer radioactive half-life (110 min) vs. the half-life of carbon-11 acetate (20.4 min). Furthermore, (18)F-FAC showed a rapid clearance from liver and extensive excretion to bile and urine in comparison with carbon-11 acetate, therefore this tracer may be a useful alternative to C-11 acetate for the detection of prostate tumors by PET.

Display Name: 18-F-fluoroacetate

Label: 18-F-fluoroacetate

NCI Thesaurus Code: C96236 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL429016  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(18)F-FAC
18-F-fluoroacetate
Fluorine F 18 Fluoroacetate

External Source Codes: 
PDQ Closed Trial Search ID 698007
PDQ Open Trial Search ID 698007 (check for NCI PDQ open clinical trial info)
NCI META CUI CL429016

Other Properties:
Name Value (qualifiers indented underneath)
code C96236
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C96236

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