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Version: 17.06d (Release date: 2017-06-26)
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Fluorine F 18 DCFBC (Code C96234)

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Terms & Properties

Preferred Name: Fluorine F 18 DCFBC

Definition: A radioconjugate containing a low molecular weight tracer, DCFBC, specific for prostate-specific membrane antigen (PSMA) and labeled with the positron-emitting isotope fluorine F 18 with potential prostate tumor imaging upon positron emission tomography (PET). Upon administration, the DCFBC moiety of fluorine F 18 DCFBC specifically targets and binds to the tumor associated antigen PSMA, thereby allowing the visualization of tumor cells expressing PSMA upon PET. PSMA is a transmembrane glycoprotein highly expressed on malignant prostate epithelial cells and vascular endothelial cells of various solid tumors.

Display Name: Fluorine F 18 DCFBC

Label: Fluorine F 18 DCFBC

NCI Thesaurus Code: C96234 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2604127  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
18F-DCFBC
[18]F-DCFBC
Fluorine F 18 DCFBC
N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-4-[18F]fluorobenzyl-L-cysteine

External Source Codes: 
PDQ Closed Trial Search ID 697880
PDQ Open Trial Search ID 697880 (check for NCI PDQ open clinical trial info)
UMLS CUI C2604127

Other Properties:
     Name Value (qualifiers indented underneath)
code C96234
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C96234

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