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Version: 17.06d (Release date: 2017-06-26)
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Muscadine Grape Skin Extract (Code C96231)

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Terms & Properties

Preferred Name: Muscadine Grape Skin Extract

Definition: A nutritional supplement containing an extract of the skin of Muscadine grape (Vitis rotundifolia), with anti-inflammatory, antioxidant and potential chemopreventive activities. The skin extract of the muscadine grape contains numerous phytochemicals including hydrolyzable tannins and flavonoids, such as anthocyanin 3,5-diglucosides, quercetin, myricetin, and kaempferol glycosides. Upon administration, muscadine grape skin extract (MSKE) appears to inhibit PI3K/Akt and MAPK signaling, eventually leading to apoptosis and a reduction in tumor cell proliferation.

Display Name: Muscadine Grape Skin Extract

Label: Muscadine Grape Skin Extract

NCI Thesaurus Code: C96231 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL429013  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
MSKE
Muscadine Grape Skin Extract

External Source Codes: 
PDQ Closed Trial Search ID 697625
PDQ Open Trial Search ID 697625 (check for NCI PDQ open clinical trial info)
NCI META CUI CL429013

Other Properties:
     Name Value (qualifiers indented underneath)
code C96231
Contributing_Source CTRP
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C96231

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