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Version: 17.06d (Release date: 2017-06-26)
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Melan-A/MAGE-3.DP4 Peptide Vaccine (Code C96041)

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Terms & Properties

Preferred Name: Melan-A/MAGE-3.DP4 Peptide Vaccine

Definition: A cancer vaccine consisting of a peptide derived from the melanocyte differentiation antigen Melan-A (or MART-1) and the human leukocyte antigen HLA-DP4-restricted human melanoma antigen 3 (MAGE-3.DP4), with potential immunostimulating and antineoplastic activities. Upon administration, Melan-A/MAGE-3.DP4 peptide vaccine may stimulate the immune system to mount a cytotoxic T-cell (CTL) response against tumor cells expressing Melan-A and MAGE-3, resulting in tumor cell lysis. The tumor associated antigens Melan-A and MAGE-3 are overexpressed in a variety of cancer cell types.

Label: Melan-A/MAGE-3.DP4 Peptide Vaccine

NCI Thesaurus Code: C96041 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL428375  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Melan-A/MAGE-3.DP4 Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 697136
PDQ Open Trial Search ID 697136 (check for NCI PDQ open clinical trial info)
NCI META CUI CL428375

Other Properties:
     Name Value (qualifiers indented underneath)
code C96041
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C96041

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