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Version: 17.06d (Release date: 2017-06-26)
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Paclitaxel Injection Concentrate for Nanodispersion (Code C96037)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Paclitaxel Injection Concentrate for Nanodispersion

Definition: A nanoparticle-based injectable concentrate containing the water-insoluble taxane paclitaxel, with potential antineoplastic activity. Upon reconstitution and administration, paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. Compared to paclitaxel alone, the nanodispersion-based formulation uses less toxic solvents and allows for administration of higher doses resulting in higher concentrations of paclitaxel at the tumor site, and an increased safety profile.

Display Name: Paclitaxel Injection Concentrate for Nanodispersion

Label: Paclitaxel Injection Concentrate for Nanodispersion

NCI Thesaurus Code: C96037 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL428371  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Paclitaxel Injection Concentrate for Nanodispersion
PICN

External Source Codes: 
PDQ Closed Trial Search ID 696555
PDQ Open Trial Search ID 696555 (check for NCI PDQ open clinical trial info)
NCI META CUI CL428371

Other Properties:
     Name Value (qualifiers indented underneath)
code C96037
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C96037

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