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Version: 16.11d (Release date: 2016-11-28)
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Freeze-dried Black Raspberry Bioadhesive Gel (Code C95770)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Freeze-dried Black Raspberry Bioadhesive Gel

Definition: A bioadhesive gel containing 10% freeze-dried black raspberries (FBR) with potential chemopreventive and antioxidant activities. The four main constituent black raspberry anthocyanins that contribute significantly to the chemopreventive effects are cyanidin 3-glucoside (C3GLU), cyanidin 3-rutinoside (C3RUT), cyanidin 3-sambubioside (C3SAM) and cyanidin 3-(2(G)-xylosyl) rutinoside (C3XRUT). Upon mucosal application, the anthocyanins from the gel penetrate the oral mucosa and are able to modulate expression of certain proapoptotic and terminal differentiation genes, and reduce the expression of epithelial cyclooxygenase-2 (COX-2) protein. In addition, this gel may also reduce vascular densities in the superficial connective tissues.

Display Name: Freeze-dried Black Raspberry Bioadhesive Gel

Label: Freeze-dried Black Raspberry Bioadhesive Gel

NCI Thesaurus Code: C95770 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL428212  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Freeze-dried Black Raspberry Bioadhesive Gel

External Source Codes: 
PDQ Closed Trial Search ID 685202
PDQ Open Trial Search ID 685202 (check for NCI PDQ open clinical trial info)
NCI META CUI CL428212

Other Properties:
Name Value (qualifiers indented underneath)
code C95770
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C95770

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