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Version: 17.06d (Release date: 2017-06-26)
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MELITAC 12.1 Peptide Vaccine (Code C95741)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: MELITAC 12.1 Peptide Vaccine

Definition: A peptide cancer vaccine consisting of an emulsion of a mixture of 12 class I MHC-restricted melanoma peptides and a class II MHC-restricted tetanus toxoid helper peptide, with potential immunostimulating and antineoplastic activities. Upon administration, the MELITAC 12.1 peptide vaccine may stimulate the host immune system to mount a cytotoxic T-cell response against tumor cells expressing the melanoma peptide antigens, resulting in tumor cell lysis. The melanoma peptides contained in the vaccine are upregulated in melanoma cancer cells.

Display Name: MELITAC 12.1 Peptide Vaccine

Label: MELITAC 12.1 Peptide Vaccine

NCI Thesaurus Code: C95741 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL428198  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
MELITAC 12.1 Peptide Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 691982
PDQ Open Trial Search ID 691982 (check for NCI PDQ open clinical trial info)
NCI META CUI CL428198

Other Properties:
     Name Value (qualifiers indented underneath)
code C95741
Contributing_Source CTRP
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C95741

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