skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Timolol Maleate Gel Forming Solution (Code C95714)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Timolol Maleate Gel Forming Solution

Definition: A gel forming solution containing the maleate salt of timolol, a propanolamine derivative and a non-selective beta-adrenergic antagonist, with intraocular pressure-reducing activity. Although the precise mechanism of action of timolol's ocular hypotensive action is not clearly established at this time, studies suggest that it may be the result of decreased aqueous humor production (possibly by reduction of blood flow to the ciliary processes and cAMP synthesis) as well as a slight increase in outflow facility. Timolol gel-forming solution can potentially be used topically as well, in the prevention of the neoangiogenesis that may occur following pulsed dye laser treatment of port wine stains.

Label: Timolol Maleate Gel Forming Solution

NCI Thesaurus Code: C95714 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0723753  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(-)-1-(tert-butylamino)-3-[(4-morpholino-1,2,5-thiadiazol-3-yl)oxy]-2-propanol Maleate (1:1) (Salt)
Timolol Maleate Gel Forming Solution
Timoptic-XE

External Source Codes: 
PDQ Closed Trial Search ID 693407
PDQ Open Trial Search ID 693407 (check for NCI PDQ open clinical trial info)
UMLS CUI C0723753

Other Properties:
     Name Value (qualifiers indented underneath)
code C95714
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C95714

Mainbox Bottom