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Version: 16.10e (Release date: 2016-10-31)
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Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8 (Code C95698)

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Terms & Properties

Preferred Name: Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8

Definition: A radioimmunoconjugate containing the murine IgG1 anti-CD45 monoclonal antibody (MoAb) BC8 labeled with yttrium 90 (Y90), with potential immunotherapeutic activity. Yttrium Y 90 anti-CD45 monoclonal antibody BC8 binds to CD45 antigen, a receptor protein-tyrosine phosphatase expressed on the surface of both normal and malignant hematopoietic cells. After binding and internalization by CD45-expressing tumor cells, this agent may deliver a cytotoxic dose of beta radiation.

Display Name: Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8

Label: Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8

NCI Thesaurus Code: C95698 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL428164  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
90Y Anti-CD45 MoAb BC8
Yttrium Y 90 Anti-CD45 Monoclonal Antibody BC8

External Source Codes: 
PDQ Closed Trial Search ID 688830
PDQ Open Trial Search ID 688830 (check for NCI PDQ open clinical trial info)
NCI META CUI CL428164

Other Properties:
Name Value (qualifiers indented underneath)
code C95698
Contributing_Source CTRP
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C95698

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