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Version: 17.06d (Release date: 2017-06-26)
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Racotumomab (Code C95024)

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Terms & Properties

Preferred Name: Racotumomab

Definition: An anti-idiotype murine monoclonal antibody (MoAb) specific to P3 MoAb with anti-metastatic effect. Racotumomab binds to the idiotype region of P3 MoAb and functionally mimics the three-dimensional structure of N-glycolyl ceramides of mono-sialyl lactose, the antigenic target of P3. As a result, this anti-idiotype antibody may stimulate the host immune system to elicit humoral and cellular immune responses against tumor cells expressing NeuGc-GM3 gangliosides, which are expressed in a wide variety of tumor cells.

Label: Racotumomab

NCI Thesaurus Code: C95024 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2986854  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Anti-P3 Antibody Idiotype Monoclonal Antibody 1E10
MoAb 1E10
RACOTUMOMAB
Racotumomab

External Source Codes: 
CAS Registry Number 946832-34-4 (see NLM ChemIDplus info)
FDA UNII Code 52G405U1E5
PDQ Closed Trial Search ID 689646
PDQ Open Trial Search ID 689646 (check for NCI PDQ open clinical trial info)
UMLS CUI C2986854

Other Properties:
     Name Value (qualifiers indented underneath)
code C95024
Contributing_Source FDA
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C95024

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