skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Pentosan Polysulfate Sodium (Code C946)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Pentosan Polysulfate Sodium

Definition: The sodium salt of a semisynthetic heparin-like glucosaminoglycan. Although its mechanism of action is unknown, pentosan polysulfate may act as a buffer to control cell permeability by preventing irritating solutes from reaching cells coated with it. Administered orally, excreted pentosan polysulfate adheres to the urinary bladder wall, preventing irritants from entering bladder cells and the development or progression of interstitial cystitis (IC), a complication of some chemotherapies. This agent also exhibits anticoagulant and fibrinolytic properties.

Label: Pentosan Polysulfate Sodium

NCI Thesaurus Code: C946 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0524684  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Cartrophen
Elmiron
Fibrase
Fibrezym
Fibrocid
Hemoclar
HOE-BAY 946
Pentosan
Pentosan Polysulfate Sodium
PENTOSAN POLYSULFATE SODIUM
Sodium Pentosan Polysulfate
Sodium Xylan Polysulfate
Tavan SP-54
Thrombocid

External Source Codes: 
CAS Registry Number 140207-93-8 (see NLM ChemIDplus info)
FDA UNII Code 914032762Y
PDQ Closed Trial Search ID 40350
PDQ Open Trial Search ID 40350 (check for NCI PDQ open clinical trial info)
UMLS CUI C0524684

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula (C5H6Na2O10S2)n
code C946
Contributing_Source FDA
Legacy_Concept_Name Pentosan_Polysulfate_Sodium
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C946

Mainbox Bottom