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Version: 17.12d (Release date: 2017-12-26)
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Anti-TA-MUC1 Monoclonal Antibody PankoMab (Code C94220)

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Terms & Properties

Preferred Name: Anti-TA-MUC1 Monoclonal Antibody PankoMab

Definition: A humanized monoclonal antibody recognizing the tumor-specific epitope of mucin-1 (TA-MUC1), with potential antineoplastic activity. Anti-TA-MUC1 monoclonal antibody PankoMab targets and binds to the TA-MUC1 epitopes expressed on the cell surface of tumor cells, thereby potentially activating the immune system to induce an antibody-dependent cellular cytotoxicity (ADCC) against the TA-MUC1-expressing tumor cells. TA-MUC1 is designated to MUC1 epitopes with O-glycosylated carbohydrate-induced conformational structures that are tumor-specific, thereby enabling PankoMab to differentiate between tumor MUC1 and non-tumor MUC1 epitopes.

Label: Anti-TA-MUC1 Monoclonal Antibody PankoMab

NCI Thesaurus Code: C94220 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2986405  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Anti-TA-MUC1 Monoclonal Antibody PankoMab

External Source Codes: 
PDQ Closed Trial Search ID 687630
PDQ Open Trial Search ID 687630 (check for NCI PDQ open clinical trial info)
UMLS CUI C2986405

Other Properties:
     Name Value (qualifiers indented underneath)
code C94220
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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