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Version: 16.11d (Release date: 2016-11-28)
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Vinblastine Sulfate (Code C931)

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Terms & Properties

Preferred Name: Vinblastine Sulfate

Definition: The sulfate salt of vinblastine, a natural alkaloid isolated from the plant Catharanthus roseus (Madagascar periwinkle) with antineoplastic properties. Vinblastine disrupts microtubule formation and function during mitosis and interferes with glutamic acid metabolism. (NCI04)

NCI-GLOSS Definition: A drug used with other drugs to treat several types of cancer, including advanced Hodgkin lymphoma and advanced testicular germinal-cell cancers. It is also being studied in the treatment of other types of cancer. Velban comes from the periwinkle plant Vinca rosea Linn. It blocks cell growth by stopping cell division and may kill cancer cells. It is a type of vinca alkaloid and a type of antimitotic agent.

Display Name: Vinblastine Sulfate

Label: Vinblastine Sulfate

NCI Thesaurus Code: C931 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0728761  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
29060-LE
29060 LE
Exal
Velban
Velbe
Velsar
Vinblastine Sulfate
VINBLASTINE SULFATE
vinblastine sulfate
VINCALEUKOBLASTINE

External Source Codes: 
CAS Registry Number 143-67-9 (see NLM ChemIDplus info)
FDA UNII Code N00W22YO2B
ChEBI ID CHEBI:9984 (see ChEBI info)
NSC Code 49842 (see NCI DTP info)
PDQ Closed Trial Search ID 688303
PDQ Open Trial Search ID 688303 (check for NCI PDQ open clinical trial info)
UMLS CUI C0728761

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C46H58N4O9.H2O4S
code C931
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Vinblastine_Sulfate
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C931

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