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Version: 17.06d (Release date: 2017-06-26)
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Vidarabine (Code C929)

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Terms & Properties

Preferred Name: Vidarabine

Definition: A nucleoside analog with activity against herpes simplex virus and varicella zoster virus. Vidarabine is converted to a monophosphate by viral thymidine kinase and is further modified to a triphosphate form by host enzymes. Vidarabine triphosphate directly inhibits DNA polymerase and also acts as a chain terminator in DNA replication.

Label: Vidarabine

NCI Thesaurus Code: C929 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0042646  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
9-Beta-D-arabinofuranosyl-9H-purine-6-amine Monohydrate
9-Beta-D-arabinofuranosyladenine Monohydrate
Adenine Arabinoside
Ara-A
Araadenosine
Arabinosyladenine
Arasena-A
Beta Ara-A
CI-673
Spongoadenosine
VIDARABINE
Vidarabine
Vira-A

External Source Codes: 
CAS Registry Number 24356-66-9 (see NLM ChemIDplus info)
FDA UNII Code FA2DM6879K
ChEBI ID CHEBI:9978 (see ChEBI info)
NSC Code 404241 (see NCI DTP info)
PDQ Closed Trial Search ID 39150
PDQ Open Trial Search ID 39150 (check for NCI PDQ open clinical trial info)
UMLS CUI C0042646

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C10H13N5O4.H2O
code C929
Contributing_Source FDA
Legacy_Concept_Name Vidarabine
Semantic_Type Nucleic Acid, Nucleoside, or Nucleotide
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C929

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