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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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P-cadherin Antagonist PF-03732010 (Code C91723)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: P-cadherin Antagonist PF-03732010

Definition: An agent that inhibits P-cadherin (cdh3), with potential antineoplastic activity. PF-03732010 binds to and inhibits the activity of p-cadherin. Inhibition of the activity of p-cadherin may inhibit tumor cell invasion and proliferation in p-cadherin expressing tumor cells. P-cadherin, a cell-surface protein and member of the cadherin family, is overexpressed in a variety of solid tumors, and plays a role in cell adhesion, motility, invasion and proliferation.

Label: P-cadherin Antagonist PF-03732010

NCI Thesaurus Code: C91723 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C3179737  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
P-cadherin Antagonist PF-03732010

External Source Codes: 
PDQ Closed Trial Search ID 580366
PDQ Open Trial Search ID 580366 (check for NCI PDQ open clinical trial info)
UMLS CUI C3179737

Other Properties:
     Name Value (qualifiers indented underneath)
code C91723
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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