skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.08d (Release date: 2017-08-28)
SearchBox Top
SearchBox Bottom
Trebananib (Code C91711)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Trebananib

Definition: An angiopoietin (Ang) 1 and 2 neutralizing peptibody, with potential antiangiogenic activity. AMG 386 targets and binds to Ang1 and Ang2, thereby preventing the interaction of the angiopoietins with their target tie2 receptors. This may inhibit angiogenesis and may eventually lead to an inhibition of tumor cell proliferation.

Display Name: Trebananib

Label: Trebananib

NCI Thesaurus Code: C91711 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1541521  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AMG 386
Angiopoietin 1/2-Neutralizing Peptibody AMG 386

External Source Codes: 
CAS Registry Number 894356-79-7 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 423474
PDQ Open Trial Search ID 423474 (check for NCI PDQ open clinical trial info)
UMLS CUI C1541521

Other Properties:
     Name Value (qualifiers indented underneath)
code C91711
Contributing_Source CTRP
Contributing_Source FDA
Semantic_Type Amino Acid, Peptide, or Protein
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


Mainbox Bottom