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Version: 17.06d (Release date: 2017-06-26)
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Fluorine F-18 6-Fluorodopamine (Code C91706)

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Terms & Properties

Preferred Name: Fluorine F-18 6-Fluorodopamine

Definition: A radioconjugate consisting of 6-fluorodopamine labeled with fluorine F18 (6-[18F]FDA), with potential diagnostic activity. Upon administration, 6-[18F]FDA is taken up by presynaptic sympathetic nerve endings via the norepinephrine transporter (NET) uptake-1. Once inside, 6-[18F]FDA is rapidly converted by dopamine-beta-hydroxylase into 6-[18F]fluoronorepinephrine (6-[18F]FNE) and stored into neuronal storage vesicles. Upon positron emission tomographic (PET) scanning of the F18, sympathetic innervated regions can be visualized, such as those in pheochromocytoma.

Label: Fluorine F-18 6-Fluorodopamine

NCI Thesaurus Code: C91706 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1541202  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
[18F]-6F-DA
[18F]-6F-dopamine
Fluorine F-18 6-Fluorodopamine

External Source Codes: 
PDQ Closed Trial Search ID 363614
PDQ Open Trial Search ID 363614 (check for NCI PDQ open clinical trial info)
UMLS CUI C1541202

Other Properties:
     Name Value (qualifiers indented underneath)
code C91706
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C91706

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