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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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Oncolytic Newcastle Disease Virus (Code C91700)

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Terms & Properties

Preferred Name: Oncolytic Newcastle Disease Virus

Definition: An oncolytic viral agent containing the oncolytic, live-attenuated strain of the paramyxovirus Newcastle disease virus (NDV), with potential antineoplastic activity. Upon administration, NDV specifically infects and replicates in cancer cells. This may result in a direct cytotoxic effect involving the lysis of tumor cells via apoptotic mechanisms and may eventually lead to an inhibition of cancer cell proliferation.

Label: Oncolytic Newcastle Disease Virus

NCI Thesaurus Code: C91700 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL422080  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Oncolytic NDV
Oncolytic Newcastle Disease Virus

External Source Codes: 
PDQ Closed Trial Search ID 257613
PDQ Open Trial Search ID 257613 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C91700
Semantic_Type Pharmacologic Substance
Semantic_Type Virus

Additional Concept Data: 
Defined Fully by Roles: No  


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