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Version: 16.11d (Release date: 2016-11-28)
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Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells (Code C91379)

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Terms & Properties

Preferred Name: Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells

Definition: A cell-based cancer vaccine composed of autologous dendritic cells (DCs) pulsed with corpses of apoptotic leukemic cells, with potential immunostimulatory and antineoplastic activities. Upon vaccination, autologous dendritic cells pulsed with leukemic apoptotic corpse may activate the immune system to mount an anti-tumoral cytotoxic T-lymphocyte (CTL) response against leukemic cells expressing leukemia-associated antigens, which may result in leukemic cell lysis and inhibition of tumor cell growth. Apoptotic tumor cell corpses contain an array of tumor associated antigens (TAAs).

Label: Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells

NCI Thesaurus Code: C91379 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL421629  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Leukemic Apoptotic Corpse-Pulsed Autologous Dendritic Cells

External Source Codes: 
PDQ Closed Trial Search ID 680606
PDQ Open Trial Search ID 680606 (check for NCI PDQ open clinical trial info)
NCI META CUI CL421629

Other Properties:
Name Value (qualifiers indented underneath)
code C91379
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C91379

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