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Version: 17.06d (Release date: 2017-06-26)
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Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine (Code C91378)

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Terms & Properties

Preferred Name: Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine

Definition: A cell-based cancer vaccine comprised of autologous dendritic cells pulsed with four alpha-fetoprotein (AFP) peptides, with potential immunostimulatory and antineoplastic activities. Upon administration, AFP peptide-pulsed autologous dendritic cell vaccine may stimulate anti-tumoral cytotoxic T lymphocyte (CTL) and antibody responses against AFP-expressing cancer cells, resulting in tumor cell lysis. AFP is overexpressed in a variety of cancer cells.

Label: Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine

NCI Thesaurus Code: C91378 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL421594  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Alpha-fetoprotein Peptide-Pulsed Autologous Dendritic Cell Vaccine

External Source Codes: 
PDQ Closed Trial Search ID 674920
PDQ Open Trial Search ID 674920 (check for NCI PDQ open clinical trial info)
NCI META CUI CL421594

Other Properties:
     Name Value (qualifiers indented underneath)
code C91378
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C91378

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