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Version: 17.06d (Release date: 2017-06-26)
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Deuterium Oxide (Code C91099)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Deuterium Oxide

Definition: A stable, non-radioactive isotopic form of water, containing 2 atoms of deuterium (D) and one atom of oxygen (2D2O), with DNA-labeling activity. Upon ingestion of deuterium oxide, 2H is incorporated into the deoxyribose moiety of DNA of newly divided cells. Rapidly dividing cells, as in the case of B-cell chronic lymphocytic leukemia (B-CLL), can be labeled with deuterium oxide and measured using gas chromatography and/or mass spectrometry.

Display Name: Deuterium Oxide

Label: Deuterium Oxide

NCI Thesaurus Code: C91099 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0011745  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Deuterium Oxide
DEUTERIUM OXIDE
Heavy Water

External Source Codes: 
CAS Registry Number 7789-20-0 (see NLM ChemIDplus info)
FDA UNII Code J65BV539M3
ChEBI ID CHEBI:41981 (see ChEBI info)
PDQ Closed Trial Search ID 672563
PDQ Open Trial Search ID 672563 (check for NCI PDQ open clinical trial info)
UMLS CUI C0011745

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula D2O
code C91099
Contributing_Source CTRP
Contributing_Source FDA
Semantic_Type Inorganic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C91099

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