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Version: 16.11d (Release date: 2016-11-28)
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Ulipristal Acetate (Code C91057)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Ulipristal Acetate

Definition: An orally bioavailable, acetate salt of ulipristal, a selective progesterone receptor modulator with anti-progesterone activity. Ulipristal binds to the progesterone receptor (PR), thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system. As a result, this agent may suppress the growth of uterine leiomyomatosis. Furthermore, by inhibiting or delaying ovulation and effecting endometrial tissue, ulipristal can be used as an emergency contraception

Label: Ulipristal Acetate

NCI Thesaurus Code: C91057 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2723461  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
11-beta-17-(acetyloxy)-11-(4-(dimethylamino)phenyl)-19-norpregna-4,9-diene-3,20-dione
17-alpha-acetoxy-11-beta-(4-dimethylaminophenyl)-19-norpregna-4,9-dien-3,20-dione
CDB-2914
Ella
PGL-4001
RTI-3021-012
ULIPRISTAL ACETATE
Ulipristal Acetate
VA-2914

External Source Codes: 
CAS Registry Number 126784-99-4 (see NLM ChemIDplus info)
FDA UNII Code YF7V70N02B
PDQ Closed Trial Search ID 729448
PDQ Open Trial Search ID 729448 (check for NCI PDQ open clinical trial info)
PubMedID Primary Reference 22296076 (see PubMed Primary Reference info)
UMLS CUI C2723461

Other Properties:
Name Value (qualifiers indented underneath)
Chemical_Formula C30H37NO4
code C91057
Contributing_Source FDA
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C91057

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