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Version: 16.11d (Release date: 2016-11-28)
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Fluorine F-18 Fluoropaclitaxel (Code C90580)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Fluorine F-18 Fluoropaclitaxel

Definition: A radiotracer containing paclitaxel labeled with the radioisotope fluorine F18 with potential use as an imaging agent. After cellular uptake, the paclitaxel moiety of fluorine F18 fluoropaclitaxel binds to tubulin. Upon uptake, the radioisotope moiety may be detected using positron emission tomography (PET), thereby allowing imaging and quantification of the biodistribution of paclitaxel. This could identify multidrug resistant (MDR) status of tumor cells and select patients that will likely respond to paclitaxel treatment.

Display Name: Fluorine F-18 Fluoropaclitaxel

Label: Fluorine F-18 Fluoropaclitaxel

NCI Thesaurus Code: C90580 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL421241  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
18F-FPAC
Fluorine F-18 Fluoropaclitaxel

External Source Codes: 
PDQ Closed Trial Search ID 668863
PDQ Open Trial Search ID 668863 (check for NCI PDQ open clinical trial info)
NCI META CUI CL421241

Other Properties:
Name Value (qualifiers indented underneath)
code C90580
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C90580

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