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Version: 17.06d (Release date: 2017-06-26)
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DCR Ligand-Bearing Liposome-Encapsulated Melanoma Antigens Vaccine (Code C90543)

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Terms & Properties

Preferred Name: DCR Ligand-Bearing Liposome-Encapsulated Melanoma Antigens Vaccine

Definition: A cancer cell-based vaccine containing liposome encapsulated melanoma antigens and an immunomodulatory factor, attached, via a metal chelator, to a dendritic cell receptor (DCR) ligand-containing a metal-affinity tag, with potential immunomodulating and antineoplastic activity. Upon intravenous administration of DCR ligand-bearing liposome-encapsulated melanoma antigens vaccine, the DCR ligand moiety of this vaccine targets receptors on dendritic cells (DCs), thereby presenting the antigens to DCs which may, in turn, stimulate the DCs and may activate the immune system to mount a cytotoxic T lymphocyte (CTL) response against melanoma cancer cell associated antigens.

Label: DCR Ligand-Bearing Liposome-Encapsulated Melanoma Antigens Vaccine

NCI Thesaurus Code: C90543 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL416224  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
DCR Ligand-Bearing Liposome-Encapsulated Melanoma Antigens Vaccine
Dendritic Cell Receptor Ligand-Bearing Liposome-Encapsulated Melanoma Antigens Vaccine
Lipovaxin-MM

External Source Codes: 
PDQ Closed Trial Search ID 665353
PDQ Open Trial Search ID 665353 (check for NCI PDQ open clinical trial info)
NCI META CUI CL416224

Other Properties:
     Name Value (qualifiers indented underneath)
code C90543
Semantic_Type Immunologic Factor
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C90543

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