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Version: 17.08d (Release date: 2017-08-28)
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Nicotine Lozenge (Code C90531)

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Terms & Properties

Preferred Name: Nicotine Lozenge

Definition: A lozenge preparation containing the alkaloid nicotine with nicotine replacement activity. Upon administration of the lozenge, nicotine is released and, although nicotine binds to nicotinic cholinergic receptors at the autonomic ganglia, adrenal medulla and at neuromuscular junctions as well, the binding of nicotine to the receptors in the central nervous system (CNS) appears to be responsible for the addictive nature of nicotine. Binding to CNS nicotinic acetylcholine receptors causes the release of the neurotransmitter dopamine which appears to be responsible for the addiction of nicotine. Administration of nicotine may prevent nicotine craving and may help with the withdrawal symptoms associated with smoking cessation.

NCI-GLOSS Definition: A hard candy-like tablet that contains a small dose of nicotine. The nicotine is absorbed through the lining of the mouth and goes into the blood. This helps stop nicotine cravings, and relieves symptoms that occur when a person is trying to quit smoking. A prescription is not needed for nicotine lozenges.

Display Name: Nicotine Lozenge

Label: Nicotine Lozenge

NCI Thesaurus Code: C90531 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C1171947  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Nicotine Lozenge
nicotine lozenge

External Source Codes: 
PDQ Closed Trial Search ID 662920
PDQ Open Trial Search ID 662920 (check for NCI PDQ open clinical trial info)
UMLS CUI C1171947

Other Properties:
     Name Value (qualifiers indented underneath)
code C90531
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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