skip navigation links
National Cancer Institute
EVS Logo NCI Term Browser Enterprise Vocabulary Services
Terminologies Value Sets Mappings
Version: 17.06d (Release date: 2017-06-26)
SearchBox Top
SearchBox Bottom
Iodine I-123 ADAM (Code C88319)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Iodine I-123 ADAM

Definition: A radiopharmaceutical containing the serotonin transporter (SERT) ligand ADAM [2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine] labeled with the radioisotope iodine I 123, with SERT-binding and radioisotope activities. Upon administration, iodine I 123 ADAM selectively binds to SERT-expressing cells; subsequently, SERT-expressing tissues may be visualized using single photon emission computed tomography (SPECT). SERT is a monamine transporter protein found in the membranes of neurons and platelets; in neurons it transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons, terminating serotonin's function.

Display Name: Iodine I-123 ADAM

Label: Iodine I-123 ADAM

NCI Thesaurus Code: C88319 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL413579  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
ADAM I-123
Iodine-123-labeled 2-((2-((dimethylamino)methyl)phenyl)thio)-5-iodophenylamine
Iodine I-123 ADAM

External Source Codes: 
CAS Registry Number 305352-16-3 (see NLM ChemIDplus info)
PDQ Closed Trial Search ID 660864
PDQ Open Trial Search ID 660864 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C15H17IN2S
code C88319
Contributing_Source CTRP
Contributing_Source FDA
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


Mainbox Bottom