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National Cancer Institute
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Version: 17.06d (Release date: 2017-06-26)
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HSV-1 HF10 (Code C88318)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: HSV-1 HF10

Definition: A non-engineered, naturally oncolytic, replication-competent spontaneous herpes simplex virus (HSV) type I mutant variant. Upon intratumoral injection, HSV1 HF10 transfects, replicates in, and lyses rapidly dividing cells such as tumor cells. In addition, this agent may increase host immune responses that may kill non-infected tumor cells.

Display Name: HSV-1 HF10

Label: HSV-1 HF10

NCI Thesaurus Code: C88318 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL413628  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Herpes Simplex Virus Type 1 HF10
HSV-1 HF10

External Source Codes: 
PDQ Closed Trial Search ID 660850
PDQ Open Trial Search ID 660850 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C88318
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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