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Version: 17.10e (Release date: 2017-10-30)
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Ramosetron Hydrochloride (Code C88299)

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Terms & Properties

Preferred Name: Ramosetron Hydrochloride

Definition: The hydrochloride salt of ramosetron, a selective serotonin (5-HT) receptor antagonist with potential antiemetic activity. Upon administration, ramosetron selectively binds to and blocks the activity of 5-HT subtype 3 (5-HT3) receptors located in the vagus nerve terminal and in the vomiting center in the central nervous system (CNS), suppressing chemotherapy-induced nausea and vomiting.

Label: Ramosetron Hydrochloride

NCI Thesaurus Code: C88299 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0526951  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(R)-5-((1-Methyl-3-indolyl)carbonyl)-4,5,6,7-tetrahydro-1H-benzimidazole Hydrochloride
Ramosetron Hydrochloride

External Source Codes: 
CAS Registry Number 132907-72-3 (see NLM ChemIDplus info)
FDA UNII Code 9551LHD87E
PDQ Closed Trial Search ID 658906
PDQ Open Trial Search ID 658906 (check for NCI PDQ open clinical trial info)
UMLS CUI C0526951

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C17H17N3O.ClH
code C88299
Contributing_Source FDA
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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