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National Cancer Institute
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Version: 16.11d (Release date: 2016-11-28)
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Short Chain Fatty Acid HQK-1004 (Code C88290)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: Short Chain Fatty Acid HQK-1004

Definition: A short chain fatty acid (SCFA) with potential herpes simplex virus thymidine kinase gene (HSV-TK)-inducing activity. Upon administration, short chain fatty acid HQK-1004 may induce the expression of thymidine kinase (TK) by a silenced HSV-TK, which may activate a co-administered antiviral prodrug such as ganciclovir, resulting in the destruction of virally-infected cancer cells.

Display Name: Short Chain Fatty Acid HQK-1004

Label: Short Chain Fatty Acid HQK-1004

NCI Thesaurus Code: C88290 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL413539  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
HQK-1004
SCFA HQK-1004
Short Chain Fatty Acid HQK-1004

External Source Codes: 
PDQ Closed Trial Search ID 657494
PDQ Open Trial Search ID 657494 (check for NCI PDQ open clinical trial info)
NCI META CUI CL413539

Other Properties:
Name Value (qualifiers indented underneath)
code C88290
Contributing_Source CTRP
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C88290

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