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Version: 16.11d (Release date: 2016-11-28)
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FGFR Inhibitor AZD4547 (Code C88272)

Terms & Properties Synonym Details Relationships Mapping View All  
Terms & Properties

Preferred Name: FGFR Inhibitor AZD4547

Definition: An orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor AZD4547 binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and, so, the inhibition of tumor cell proliferation and tumor cell death. FGFR, up-regulated in many tumor cell types, is a receptor tyrosine kinase essential to tumor cellular proliferation, differentiation and survival.

Display Name: FGFR Inhibitor AZD4547

Label: FGFR Inhibitor AZD4547

NCI Thesaurus Code: C88272 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL412460  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
AZD4547
FGFR Inhibitor AZD4547

External Source Codes: 
ChEBI ID CHEBI:63453 (see ChEBI info)
PDQ Closed Trial Search ID 655951
PDQ Open Trial Search ID 655951 (check for NCI PDQ open clinical trial info)
NCI META CUI CL412460

Other Properties:
Name Value (qualifiers indented underneath)
code C88272
Contributing_Source CTRP
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C88272

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