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National Cancer Institute
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Version: 17.12d (Release date: 2017-12-26)
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Fluorine F 18 ISO-1 (Code C88265)

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Terms & Properties

Preferred Name: Fluorine F 18 ISO-1

Definition: A radioconjugate consisting of the benzamide ligand ISO-1 labeled with the radioisotope fluorine F18 with positron-emitting radioisotope activity. Upon administration, fluorine [F18]ISO-1 binds to sigma-2 receptors, located on tumor cells, allowing visualization of sigma-2 receptor-expressing tumor cells with positron emission tomography (PET). Sigma-2 receptors, expressed in a variety of normal healthy tissues such as liver, kidneys, endocrine glands, and in the central nervous system, may be overexpressed in tumor cells.

Label: Fluorine F 18 ISO-1

NCI Thesaurus Code: C88265 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: CL412443  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Fluorine F 18 ISO-1

External Source Codes: 
PDQ Closed Trial Search ID 654636
PDQ Open Trial Search ID 654636 (check for NCI PDQ open clinical trial info)

Other Properties:
     Name Value (qualifiers indented underneath)
code C88265
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  


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