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Version: 17.06d (Release date: 2017-06-26)
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Dronabinol (Code C867)

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Terms & Properties

Preferred Name: Dronabinol

Definition: An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana.

NCI-GLOSS Definition: A synthetic pill form of delta-9-tetrahydrocannabinol (THC), an active ingredient in marijuana that is used to treat nausea and vomiting associated with cancer chemotherapy.

Display Name: Dronabinol

Label: Dronabinol

NCI Thesaurus Code: C867 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0039663  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
(-)-.DELTA.9-Tetrahydrocannabinol
Abbott 40566
Delta(9)-Tetrahydrocannibinol
Delta-9-Tetrahydrocannabinol
Delta-9-THC
Delta9-THC
Delta 9-Tetrahydrocannabinol
Dronabinol
dronabinol
DRONABINOL
Marinol
SP-104
SP 104
Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol
Tetrahydrocannabinol
THC

External Source Codes: 
CAS Registry Number 1972-08-3 (see NLM ChemIDplus info)
FDA UNII Code 7J8897W37S
NSC Code 134454 (see NCI DTP info)
PDQ Closed Trial Search ID 39707
PDQ Open Trial Search ID 39707 (check for NCI PDQ open clinical trial info)
UMLS CUI C0039663

Other Properties:
     Name Value (qualifiers indented underneath)
Chemical_Formula C21H30O2
code C867
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Dronabinol
Semantic_Type Organic Chemical
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C867

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