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Version: 16.10e (Release date: 2016-10-31)
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Technetium Tc-99m Sulfur Colloid (Code C856)

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Terms & Properties

Preferred Name: Technetium Tc-99m Sulfur Colloid

Definition: A gamma-emitting colloid used in scintillation scanning of the reticuloendothelial system (RES). After intravenous administration, technetium Tc 99m sulfur colloid is phagocytized by the reticuloendothelial system and concentrated in the liver, spleen, and bone marrow; detection/localization of phagocytized gamma ray-emitting colloid is performed with a gamma-ray scintillation camera. Scintillation scanning using technetium Tc 99m colloid sulfur helps determine the distribution and function of the RES and the extent to which tumor involves the RES. The RES includes cells types that can phagocytize and sequester inert particles and vital dyes; RES cell types include macrophages or macrophage precursors, specialized endothelial cells lining the sinusoids of the liver, spleen, and bone marrow, and reticular cells of lymphatic tissue and of bone marrow.

NCI-GLOSS Definition: A substance being studied as a way to find cancer in the body. It is also used to find sentinel lymph nodes in breast cancer. It contains a radioactive substance called technetium linked to a substance called sulfur colloid. Sulfer colloid is taken up by special cells in lymph tissue, and in the liver, spleen, and bone marrow after it is injected. A machine or probe that detects radioactivity is used to find where the technetium Tc 99m sulfur colloid is in the body. It is a type of radiopharmaceutical and a type of radioimaging agent.

Display Name: Technetium Tc-99m Sulfur Colloid

Label: Technetium Tc-99m Sulfur Colloid

NCI Thesaurus Code: C856 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C0039419  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Tc-99m SC
Tc 99m Sulfur Colloid
Tc 99m sulfur colloid
Technetium Tc-99m Sulfur Colloid
TECHNETIUM TC-99M SULFUR COLLOID
Technetium Tc 99m Sulfur Colloid
technetium Tc 99m sulfur colloid

External Source Codes: 
CAS Registry Number 7704-34-9 (see NLM ChemIDplus info)
FDA UNII Code 556Q0P6PB1
PDQ Closed Trial Search ID 42818
PDQ Open Trial Search ID 42818 (check for NCI PDQ open clinical trial info)
UMLS CUI C0039419

Other Properties:
Name Value (qualifiers indented underneath)
Accepted_Therapeutic_Use_For Diagnostic imaging
Chemical_Formula S8.Tc
code C856
Contributing_Source CTRP
Contributing_Source FDA
Legacy_Concept_Name Tc_99m_Sulfur_Colloid
Semantic_Type Indicator, Reagent, or Diagnostic Aid

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C856

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