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Version: 17.06d (Release date: 2017-06-26)
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Resveratrol Formulation SRT501 (Code C85484)

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Terms & Properties

Preferred Name: Resveratrol Formulation SRT501

Definition: A proprietary formulation of resveratrol, a polyphenolic phytoalexin derived from grapes and other food products with potential antioxidant, anti-obesity, antidiabetic and chemopreventive activities. Resveratrol may activate sirtuin subtype 1 (SIRT-1). SIRT1 activation has been reported to inhibit tumorigenesis and tumor cell proliferation. SIRT-1 is a member of the silent information regulator 2 (SIR2) (or sirtuin) family of enzymes that plays an important role in mitochondrial activity and acts as a protein deacetylase. SIRT1 appears to be involved in the regulation of numerous transcription factors such as NF-kB and p53.

Label: Resveratrol Formulation SRT501

NCI Thesaurus Code: C85484 (Search for linked caDSR metadata)  (search value sets)

NCI Metathesaurus Link: C2002402  (see NCI Metathesaurus info)

Synonyms & Abbreviations: (see Synonym Details)
Resveratrol Formulation SRT501
SRT501

External Source Codes: 
PDQ Closed Trial Search ID 648245
PDQ Open Trial Search ID 648245 (check for NCI PDQ open clinical trial info)
UMLS CUI C2002402

Other Properties:
     Name Value (qualifiers indented underneath)
code C85484
Semantic_Type Pharmacologic Substance

Additional Concept Data: 
Defined Fully by Roles: No  

URL: https://ncit.nci.nih.gov/ncitbrowser/ConceptReport.jsp?dictionary=NCI_Thesaurus&code=C85484

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